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KMID : 0360119920140030228
Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
1992 Volume.14 No. 3 p.228 ~ p.236
An experimental study of the effects of bone wax on the mouse femoral bone defects




Abstract
Thistudy was to designed to evaluate the reactions of mouse femoral bone to bone wax. In sixteen mice with a strain of I. C. R. mouse weighed approximately 300 to 350g, 2.0~2.0mm sized bone defects were created drilling. Half of mice were
inserted
by
bone wax and the remainder serving as control without bone wax application. The mice were sacrified 1, 2, 6, 8 weeks after operation and block specimens were prepared for light microscopy examination.
@ES The results obtained were as follows.
@EN 1. Histologic features of tissue reaction to bone wax were the presence of inflammatory cell infiltration and multincleated giant cell.
2. Bone wax helaing from the created margin were markedly impaired by the application of bone wax.
3. Now bone formation was marrkedly decreased in bone wax application.
KEYWORD
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